ATOPIC DERMATITIS

Endogenous Types of Eczematous Dermatitis

  • Atopic dermatitis - see "Diagnosis" section

  • Seborrheic dermatitis - a common erythematous, scaling or crusting eruption that occurs in areas with a high concentration of sebacious glands, e.g., scalp, face, postauricular, presternal, and interiginous areas. In infants it often occurs as the yellow, greasy scale of "cradle cap." Seborrheic dermatitis has an early age of onset, little pruritus, a lack of atopy, and is not linked to AD.

  • Nummular eczema - a condition related to dry skin, not atopy, and IgE levels are normal. The lesions are discoid or coin-shaped, eczematous, plaques made up of tiny vesicles and papules that enlarge to become discrete, round, erythematous, lichenified, hyperpigmented patches with a diameter of >1 cm. These usually affect the extensor surfaces of the hands, arms, and legs, and there is little in the way of itching.

  • Stasis dermatitis - an eczematous eruption found on the lower leg. It is generally the result of venous insufficiency. The condition can be acute, subacute, chronic, or recurrent, and can include ulceration of the skin.

  • Perioral dermatitis - most often a disease of young women and can resemble acne. It is accompanied by a burning feeling rather than itching. The lesions are discrete, 1-3 mm. Erythematous papules, papulovesicles, and/or papulopustules that affect the chin and nasolabial folds in a symmetrical fashion, usually sparing the vermillion border. The lesions become diffusely red and can be replaced by erythematous scaling.

  • Neurodermatitis - also known as lichen simplex chronicus. It consists of chronic, localized, pruritic eruptions that result from repeated bouts of itching, scratching, and rubbing. It can occur idiopathically or be secondary to another condition such as AD, seborrheic dermatitis, contact dermatitis, lichen planus, or psoriasis. It is most commonly seen in women between the ages of 30 and 50 years. The early findings include reddened slightly edematous skin with exaggerated markings. Later in the course of the condition there are well-circumscribed itchy areas of dry, thickened, scaly, hyper- or hypopigmented skin. Generally, there is no associated atopy, the lesions are not found in the flexural areas, and the history is different from that found in AD.

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Differential Diagnosis